Foodie Pharmacology Podcast

Antibiotic resistance is one of the most pressing challenges in modern medicine, raising the risk of a return to a pre-antibiotic era where common infections become life-threatening. This week on Foodie Pharmacology, Dr. Cassandra Quave speaks with Dr. Nadine Ziemert about how scientists are turning to microbial genomes to discover the next generation of antibiotics. A professor of translational genome mining at the University of Tübingen, Nadine explains how bacteria themselves are prolific chemists, producing complex natural products that can be harnessed to fight infection. The conversation explores why traditional discovery methods have slowed, how genome mining reveals hidden “chemical dark matter” in the environment, and how computational tools are helping researchers predict new molecules before they are even isolated in the lab. From the vast, untapped diversity of soil microbes to the future potential of AI-driven discovery pipelines, this episode offers a hopeful look at how science is working to stay ahead in the race against antibiotic resistance. Learn more about Dr. Ziemert’s research on her lab’s YouTube channel.

The health of our environment underpins everything from food systems to future medicines, yet much of the damage done to nature goes unaddressed. This week on Foodie Pharmacology, Dr. Cassandra Quave speaks with Jacob Phelps about a new approach to conservation that brings science into the courtroom. Together, they explore how environmental litigation can move beyond small fines and toward holding offenders accountable for restoring damaged ecosystems, from illegal mining and deforestation to wildlife trafficking. The conversation highlights the gap between strong environmental laws on paper and their limited use in practice, and how interdisciplinary teams of scientists and lawyers are working to change that. From protecting biodiversity and safeguarding food systems to preserving resources that may hold future therapeutic value, this episode offers a powerful look at how legal action can be used as a tool to defend and repair the natural world. Learn more at https://www.conservation-litigation.org/

Spring is a time when many of us think about fresh starts and better health, including the well-being of our pets. This week on Foodie Pharmacology, Dr. Cassandra Quave speaks with Angela Ardolino about natural approaches to supporting aging dogs. Angela, a formulator and educator specializing in cannabinoids, medicinal mushrooms, and adaptogens, explains how these compounds interact with the endocannabinoid system to regulate inflammation, neurological function, and overall balance. They discuss the differences between full-spectrum hemp extracts and isolated compounds, how cannabinoids may support joint pain, seizures, and cognitive decline, and the growing interest in functional mushrooms like lion’s mane, reishi, and cordyceps for brain health of our pets. The conversation also examines what cognitive decline looks like in aging pets, the role of inflammation and the gut-brain connection, and how diet and ultra-processed pet foods may contribute to disease. From reading supplement labels to understanding ingredient sourcing and quality, this episode offers a practical framework for pet owners interested in integrative approaches to animal health. Learn more about Angela’s work at https://angelaardolino.com/

Seed oils are everywhere. From salad dressings to snack foods, they’ve become a quiet staple of the modern diet. But how did they get there, and what do we really know about their impact on human health?

This week on Foodie Pharmacology, Dr. Cassandra Quave sits down with nutritionist Cherie Calbom, MS, known as “The Juice Lady,” to unpack the rise of industrial seed oils and the debate surrounding them. Cherie shares her personal journey into nutrition, which began with a serious health crisis and led her to rethink the role of food in healing.

Together, they explore what seed oils actually are, how they are processed, and why their chemical structure makes them vulnerable to oxidation. The conversation traces their history from industrial byproducts to “heart-healthy” staples, shaped by wartime supply chains, shifting dietary guidance, and powerful marketing.

They also dig into where these oils are hiding in everyday foods, why they can be difficult to avoid even when you are trying to eat well, and how to navigate labels in a highly processed food environment.

If you’ve ever wondered what’s really in the oils lining grocery store shelves, or why this topic has become so widely debated, this episode offers a deeper look at the science, history, and real-world implications of seed oils in today’s diet. Learn more about Cherie’s work at thejuiceladycherie.com

Spring is here, and seasonal pollen along with it! This week on Foodie Pharmacology, Dr. Cassandra Quave speaks with Gary Falcetano, PA-C, AE-C, Senior Manager of Global Medical & Scientific Affairs in Allergy at Thermo Fisher Scientific and a longtime clinician and educator in asthma and immunologic disorders, about pollen food allergy syndrome and why certain fresh foods can suddenly cause itching or irritation during allergy season.

Also known as oral allergy syndrome, this condition stems from cross-reactivity between pollen proteins and similar proteins found in plant foods. Gary explains how this immune mix-up happens, why symptoms are typically limited to the mouth and throat, and why something as simple as cooking an apple can make it more tolerable.

They also cover how common this syndrome is, why it is frequently overlooked, and how clinicians distinguish it from more serious food allergies using detailed history and targeted testing. The conversation highlights the role of IgE, component-resolved diagnostics, and the importance of understanding seasonal exposure. The episode closes with practical tips for managing symptoms, from reducing pollen exposure at home to simple food preparation strategies that can make a real difference during peak allergy season.

This Foodie Pharmacology podcast is part of a special two part series sponsored by Thermo Fisher Scientific Inc. The views and opinions in this podcast are those of the presenters and represent the synthesis of science.

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