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PodcastyEdukacjaThe Biology of Trauma® With Dr. Aimie

The Biology of Trauma® With Dr. Aimie

Dr. Aimie Apigian
The Biology of Trauma® With Dr. Aimie
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  • Fear From Breast Cancer: How Two Mothers Reject ‘Normal’ & Find Freedom
    After treatment, Dirci was told by her oncologist to go back to her life as “normal.” But as she steps into the cancer support groups, everyone is in fear of remission. Melanie received the diagnosis of breast cancer, felt the fear of if treatment would get it all, and decided now was the best time for nervous system healing -not later. She finds herself on the radiation table using her somatic tools and finding a calm and a freedom that surprises the nurses.  Many people receive cancer diagnoses without anyone explaining how stress, trauma and nervous system dysregulation create the biological conditions where disease can be welcomed.  For practitioners supporting clients through cancer treatment, and for individuals navigating their own healing journey, understanding the connection between stored trauma and physical health changes everything about experiencing freedom from the fear that accompanies a diagnosis, even after successful treatment. This episode shares two stories about breast cancer and the nervous system regulation work that became essential to their ability to find freedom during and after the treatment.  You'll hear from Dirci, a mother of twins who developed breast cancer during the pandemic after years of daily overwhelm, and Melanie, whose postpartum anxiety and childhood hypervigilance preceded her diagnosis.  Both women went where their oncologists said wouldn't make a difference—yet addressing their nervous system dysregulation became the missing, foundational piece for their emotional health. Their journeys reveal what becomes possible when we heal the underlying Biology of Trauma® instead of returning to the patterns that created illness. In this episode you'll learn: [02:01] Dirci's Story: How her sister's death, twins' therapy sessions, and daily overwhelm preceded breast cancer [10:54] When Doctors Say "Go Back to Normal": Why returning to life as usual after treatment felt wrong [14:09] The Moment Everything Clicked: Discovering trauma in her body through Dr. Aimie's interview [18:30] From Information to Embodiment: How the 21 Day Journey created awareness and presence in daily life [21:04] The Transformation Others Noticed: Looking better after cancer treatment than before diagnosis [27:02] Melanie's Story: Postpartum anxiety, rage, and hypervigilance that preceded her breast cancer diagnosis [36:04] Using Rage as a Pause Button: How anger became a coping mechanism to control overwhelming environments [41:45] Going Through Treatment with Peace: Using the heart hold on the radiation table instead of panic [48:26] Tools That Don't Wear Out: Why nervous system regulation practices remain effective years later [49:40] Healing the Next Generation: Breaking intergenerational trauma patterns by regulating your own nervous system Main Takeaways: Normal Was What Made Them Sick: When doctors said "return to life as normal," both women recognized that normal—daily overwhelm, hypervigilance, pushing through exhaustion—was what had created the conditions for illness in their bodies. Too Much Too Fast and Too Little for Too Long: Dirci's story shows how these two trauma patterns combined—sudden losses and daily therapy stressors—created chronic nervous system dysregulation that manifested as breast cancer two years later. Cancer Communities Can Create More Fear: Traditional cancer support groups focused on recurrence statistics and survival rates kept both women in fear states, while trauma healing communities offered a path toward joy and aliveness instead. Awareness Creates Different Parenting: Learning to regulate her own nervous system helped Dirci recognize when her children were in sympathetic or shutdown states, allowing her to parent from understanding rather than trying to change behaviors. The Body Needs Tending During Treatment: Melanie went through radiation and biopsies with peace by using tools like the heart hold and orienting—creating connection with medical staff instead of panic. Healing Tools That Don't Wear Out: Unlike other modalities that lose effectiveness over time, the nervous system regulation tools from the 21 Day Journey remained relevant and powerful for both women years later. Moving From Hours to Presence: Dirci shifted from feeling like she never had enough hours in the day to actually being present in her life—the essence of the healing journey.   Notable Quotes: "I knew that the way my life was happening was what put me into cancer. So I needed to find help." - Dirci Souza "I don't want to have fear, I just want to support my body. I would rather be working towards finding a path to feel joy and feel alive than to take a path that brings along the fear." - Dirci Souza "Until then, I had no idea. Didn't cross my mind. Trauma. Am I traumatized? For me it was just life. What I was going through and I needed to be brave, I was surviving." - Dirci Souza "I used anxiety to fuel myself. So I would keep doing whatever it is I needed to do. That's the energy I ran on." - Melanie "I could not have imagined remaining so calm and centered going through cancer treatment. I could put my hand over my heart right there on the radiation table. That was one of my favorite moments through the whole cancer journey." - Melanie   Episode Takeaway: When oncologists say "return to life as normal" after cancer treatment, they miss a critical piece: normal was often what created the conditions for illness. Both Dirci and Melanie's stories reveal how years of nervous system dysregulation—chronic hypervigilance, pushing through exhaustion, using anxiety as fuel—created the biological environment where cancer could develop. Dysregulation multiplied by time creates disease. Their diagnoses arrived after years of too much too fast combined with too little for too long. The remarkable insight: both women looked better after cancer treatment than before diagnosis. Why? They finally addressed underlying nervous system dysregulation, not just the cancer. Simple tools like the heart hold and vu breath created immediate regulation—Melanie used the heart hold on the radiation table and experienced peace instead of panic. Most powerfully, healing your nervous system heals the next generation through co-regulation, breaking intergenerational trauma biology that manifests as chronic illness decades later. Resources/Guides: The Biology of Trauma book - Available now everywhere books are sold. Get your copy Foundational Journey - If you are ready to create your inner safety and shift your nervous system, join me and my team for this 6 week journey of practical somatic and mind-body inner child practices. Lay your foundation to do the deeper work safely and is the pre-requisite for becoming a Biology of Trauma® professional.  Related Episodes: Episode 32: What are the Ways the Body Communicates Stored Trauma? with Dr. Aimie Apigian Episode 74: Why Stored Traumas Become Syndromes & Somatic Solutions with Peter Levine Your host: Dr. Aimie Apigian, double board-certified physician (Preventive/Addiction Medicine) with master's degrees in biochemistry and public health, and author of the national bestselling book "The Biology of Trauma" (foreword by Gabor Maté) that transforms our understanding of how the body experiences and holds trauma. After foster-adopting a child during medical school sparked her journey, she desperately sought for answers that would only continue as she developed chronic health issues. Through her practitioner training, podcast, YouTube channel, and international speaking, she bridges functional medicine, attachment and trauma therapy, facilitating accelerated repair of trauma's impact on the mind, body and biology. Disclaimer: By listening to this podcast, you agree not to use this podcast as medical, psychological, or mental health advice to treat any medical or psychological condition in yourself or others. This podcast is for informational and educational purposes only and does not constitute professional advice, diagnosis, or treatment. Always consult your own physician, therapist, psychiatrist, or other qualified health provider regarding any physical or mental health issues you may be experiencing. Comment Etiquette: I would love to hear your thoughts on this episode. Please share and use your name or initials so that we can keep this space spam-free and the discussion positive😌  
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  • Understanding the Freeze Response and Brain Fog
    What if the brain fog you're experiencing isn't just tiredness—but your nervous system's way of disconnecting you from an unbearable reality? In this mini episode, Dr. Aimie Apigian answers a question from Rachel, a therapist in Seattle, about why the freeze response is associated with brain fog. Many people think of the freeze response as simply paralysis, not understanding the sophisticated biological mechanisms happening at the cellular level. This episode dives deep into the freeze response—when it happens, why it happens, and the brain inflammation that creates the disconnection and fog we experience. Understanding this biology helps us recognize when we or someone we're working with has a chronic functional freeze, so we know where to start with healing. In this episode you'll hear more about: The five steps the body takes to go into a trauma response—starting with activation and crossing the critical line of overwhelm The two reasons we cross that critical line: "too much too fast" (excessive activation) and "too little for too long" (prolonged stress without recovery) Why your nervous system decides certain situations are life threats—even when logically they're not (like being berated in residency or hearing hurtful words from someone you care about) The cellular biology of brain fog: How immune cells in your brain (microglia) unleash inflammation, cytokines, and chemokines that create the mental disconnection and fog The surreal feeling of freeze: Why voices sound distant, why you feel like you're in a daze, and why people around you seem far away even though they're right there Chronic functional freeze: The state where you're still functioning and going through life, but secretly wanting to hide, using substances like caffeine or food (especially histamine-producing foods) to push through Why anxiety is often your body fighting the freeze—using stress to stay out of shutdown, which is why relief from anxiety can sometimes make you fall into that heaviness The brain inflammation protocol: Specific nutrients and practices to keep your microglia in their resting state, including NAC, magnesium L-threonate, luteolin, GABA, resveratrol, and turmeric Ocular-cardiac reflex (eye support): A simple but powerful tool where gently pressing on closed eyes activates the vagus nerve for immediate calm Why starting with the freeze is essential—opening up the chronic functional freeze gives you more energy to dedicate to the healing journey Dr. Aimie's personal story of a biking accident and concussion—experiencing the freeze response firsthand as she regained consciousness on the sidewalk The freeze response isn't weakness or paralysis—it's your nervous system's sophisticated survival strategy when it perceives a life threat. Brain fog is always part of the freeze response, created by immune cells in your brain that help you disconnect from unbearable reality. Understanding this biology helps you recognize the freeze in yourself or others, and know that working with it is where healing must start. 🎧 Want the full conversation? This mini episode expands on Episode 142: Why Stress Isn’t Trauma: How to Spot Overwhelm and Start Healing Your Nervous System with Dr. Aimie Apigian, where Dr. Aimie explores the difference between stress and trauma responses and how to recognize when you've crossed the critical line of overwhelm.
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  • Why Stress Isn’t Trauma: How to Spot Overwhelm and Start Healing Your Nervous System with Dr. Aimie Apigian
    Why does brain inflammation happen during the freeze response? How do you explain the difference between stress and trauma to patients? What's the single most important starting point for nervous system regulation? This episode answers these critical questions while revealing why emotional eating isn't a willpower problem and introducing the simple three-day tracking tool that changes everything for healing. You'll discover the critical line of overwhelm - that invisible threshold where stress becomes trauma - and learn practical strategies you can implement immediately to support your nervous system and begin the repair process. In this episode you'll learn: [01:19] The Biggest Myth: Why confusing stress and trauma leads to minimizing experiences and self-shame  [02:11] Physician's Lens on Trauma: If it makes you sick 20 years later, it wasn't just stress  [06:04] Three Nervous System States: Understanding polyvagal theory and the critical line of overwhelm  [09:52] Brain Inflammation During Freeze: Why immune cells unleash inflammation as protective survival strategy  [13:25] Dysregulation Multiplied by Time: Why autoimmunity takes 20 years of nervous system dysregulation to appear  [14:40] Three-Day Nervous System Journal: Simple hourly tracking tool that reveals hidden patterns  [19:00] The Gut-Brain Connection: Why your gut is inseparable from brain health and trauma loops  [21:22] Emotional Eating and Functional Freeze: Understanding food's hidden functions beyond willpower  [24:40] The #1 Starting Point: Why quality sleep has greatest impact on nervous system regulation  [25:44] Aligning with Circadian Rhythm: Morning sunlight, red light therapy, and working with your body's healing strategies Main Takeaways: Stress vs. Trauma Requires Different Repair: If it makes you sick 20 years later, it was trauma requiring fundamentally different approaches than stress management The Critical Line of Overwhelm: Personal capacity threshold where activation becomes trauma and the body automatically hits emergency brake Brain Inflammation Serves Protection: Immune cells unleash inflammation during freeze to facilitate disconnection and energy conservation for survival Time Compounds Dysregulation: Autoimmunity requires approximately 20 years of nervous system dysregulation to manifest as diagnosable disease Three-Day Tracking Creates Awareness: Hourly nervous system tracking reveals patterns showing time spent in shutdown, stress, or calm aliveness Innate Healing Requires Right Conditions: Surgical incisions prove the body heals itself when blocks are removed and proper support provided Gut-Brain Creates Stuck Points: Imbalanced gut causes neurochemical problems feeding back to worsen gut issues, limiting therapy progress Food Function Reveals Need: Emotional eating serves specific purposes - staying awake, avoiding feelings, managing energy - not willpower failure Sleep Impacts Everything: Quality sleep has greatest single effect on nervous system regulation and reduces sugar cravings Notable Quotes: "If it makes you sick 20 years later, that was not just stress. That was trauma your body was experiencing in childhood. You're looking at it through the lens of your adult self now, but that's not how you were experiencing it back then." "The critical line of overwhelm is where you've done your best. Your best wasn't good enough, and hitting the wall means there's no point in trying anymore." "Brain inflammation is part of a trauma response. Sometimes it triggers it. Sometimes it's triggered by the freeze response, but they always happen together." "Dysregulation multiplied by time becomes diagnoses. It's predictable." "Track your nervous system, and you'll be amazed at how much you learn about yourself in a week."   Episode Takeaway: The critical line of overwhelm represents your personal threshold where stress becomes trauma and your body automatically engages the emergency brake. Brain inflammation during freeze is part of the deliberate survival strategy - helping you disconnect, go numb, and conserve energy for survival. The insight: dysregulation multiplied by time becomes disease. Autoimmunity takes approximately 20 years of compounded nervous system dysregulation to manifest. This explains why short-term stress doesn't cause chronic illness but prolonged trauma patterns do. The three-day nervous system journal - tracking your inner state hourly - reveals patterns invisible to both practitioners and clients. This tracking tool shows how much time you spend in each of the three states and guides targeted intervention. Quality sleep stands as the single most powerful starting point for nervous system regulation. Better sleep reduces emotional eating, decreases sugar cravings, and increases your capacity to handle stress before crossing that critical line into trauma territory. Resources/Guides: The Biology of Trauma book - Available now everywhere books are sold. Get your copy Foundational Journey - If you are ready to create your inner safety and shift your nervous system, join me and my team for this 6 week journey of practical somatic and mind-body inner child practices. Lay your foundation to do the deeper work safely and is the pre-requisite for becoming a Biology of Trauma® professional.  Related Episodes: Episode 101: Brain Inflammation: Addressing The Overlooked Gatekeeper To Trauma Release with. Dr Austin Perlmutter Your host: Dr. Aimie Apigian, double board-certified physician (Preventive/Addiction Medicine) with master's degrees in biochemistry and public health, and author of the national bestselling book "The Biology of Trauma" (foreword by Gabor Maté) that transforms our understanding of how the body experiences and holds trauma. After foster-adopting a child during medical school sparked her journey, she desperately sought for answers that would only continue as she developed chronic health issues. Through her practitioner training, podcast, YouTube channel, and international speaking, she bridges functional medicine, attachment and trauma therapy, facilitating accelerated repair of trauma's impact on the mind, body and biology. Disclaimer: By listening to this podcast, you agree not to use this podcast as medical, psychological, or mental health advice to treat any medical or psychological condition in yourself or others. This podcast is for informational and educational purposes only and does not constitute professional advice, diagnosis, or treatment. Always consult your own physician, therapist, psychiatrist, or other qualified health provider regarding any physical or mental health issues you may be experiencing. Comment Etiquette: I would love to hear your thoughts on this episode. Please share and use your name or initials so that we can keep this space spam-free and the discussion positive😌
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  • BRCA Gene Carriers: How Nervous System Dysregulation Affects Breast Cancer Risk
    What if having the same gene as your sister doesn't mean you'll have the same outcome? What if trauma and nervous system dysregulation could be the difference between expressing a genetic disease—or not? In this mini episode, Dr. Aimie Apigian answers a question from Rachel in Texas, who discovered she carries the BRCA gene mutation. Despite making the same lifestyle changes as her sister—who also has the mutation—Rachel developed breast cancer while her sister remained healthy. Why? Dr. Aimie reveals the biological mechanism that connects nervous system dysregulation to genetic expression: oxidative stress. This episode offers a scientifically grounded yet hopeful perspective on why two people with identical genetics can have vastly different health outcomes—and what you can do about it. In this episode you'll hear more about: Why BRCA mutation carriers have a 45-72% lifetime breast cancer risk (versus 12-13% in the general population)—but not everyone with the gene develops cancer The biological link between nervous system dysregulation and oxidative damage to DNA How BRCA genes interact with NRF2 antioxidant pathways, creating increased vulnerability to oxidative stress Why both sympathetic activation (stress/anxiety) and dorsal vagal shutdown (depression/numbness) decrease your body's ability to clear oxidative stress The "calm alive" state: when your body naturally engages its healing and antioxidant repair mechanisms Dana's story from The Biology of Trauma—a physician with childhood trauma who found a breast lump and learned to repair nervous system dysregulation Practical tools: why vitamin C and antioxidant-rich foods (broccoli, blueberries) matter for genetic conditions How somatic self-practices can quickly shift your nervous system state and support cellular repair Why having a genetic condition doesn't mean you're powerless—epigenetics shows us DNA expression can change Genetics load the gun, but environment and nervous system state pull the trigger. This episode is a powerful reminder that even when you carry genetic risk, your nervous system regulation, oxidative stress levels, and daily practices can dramatically influence whether those genes are expressed. Your biology is not a life sentence. 🎧 Want the full conversation? This mini episode expands on Episode 141: Can Trauma Make Genetic Disease Worse? The Role of the Nervous System, where Dr. Aimie explores hereditary conditions and why nervous system work matters even when genetics are involved.
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  • Can Trauma Make Genetic Disease Worse? The Role of the Nervous System
    Many people living with genetic conditions like MEN1, or hereditary autoimmune disorders feel trapped by their diagnosis. Practitioners often monitor and treat symptoms without addressing how trauma and nervous system dysregulation amplify those symptoms. But what if your nervous system still holds the key to how you experience your genetic condition? In this conversation, Lizzie Dunn, diagnosed at 13 with MEN1, shares how she came to my work skeptical about trauma's role in genetic disease. She discovered that her body wasn't betraying her. It was protecting her. And through nervous system regulation and somatic work, she experienced shifts she never thought possible. This episode bridges the gap between conventional medicine and trauma healing. Whether you're a practitioner working with genetic conditions or someone living with a hereditary diagnosis, you'll learn how the nervous system acts as the master conductor of your biology. In this episode you'll hear more about: [00:00:09] How nervous system regulation influences genetic disease symptoms [00:03:00] Why the nervous system sees genetic mutations as vulnerabilities that trigger faster trauma responses [00:09:00] How stored trauma creates dysregulation that amplifies all symptoms [00:14:00] Why so many people with chronic conditions live disconnected from their bodies [00:22:00] How paradox and vulnerability are essential parts of healing [00:23:40] Why generational trauma gets passed down through mitochondrial DNA [00:30:00] How healing requires working on mind, body, and biology levels simultaneously [00:36:00] Why small interventions across three areas create bigger shifts than years of single-approach work Main Takeaways: Nervous System as Master Conductor: Even with genetic conditions, the nervous system determines symptom severity by directing all physiological responses and biological adaptations Genetic Vulnerabilities Trigger Faster Trauma Responses: The nervous system sees genetic mutations as vulnerabilities, causing it to move into overwhelm and trauma biology more quickly than if no vulnerabilities existed Body Disconnection is Survival: Living in your head and disconnecting from your body is a protective mechanism to avoid overwhelming sensations of powerlessness, shame, and pain Generational Trauma Through DNA: Trauma passes down through mitochondrial DNA on the mother's side via epigenetic changes from oxidative stress, affecting gene expression in future generations Integration Creates Lasting Change: Single-approach healing (therapy alone, supplements alone, or diet alone) creates temporary shifts; addressing mind, body, and biology simultaneously creates sustainable transformation Small Hinges Move Big Doors: You don't need decades of intensive work; small interventions across three levels create remarkable shifts when done together Body Has Innate Healing Capacity: Like skin healing over surgical incisions, the body can reorganize and reset when blocks at mind, body, and biology levels are removed Notable Quotes: "Even if we have a truly genetic disease, the nervous system is still going to be influencing the degree of symptoms that we have from that." "The nervous system is what drives all the other systems, because it's what changes them, allows them to adapt to our environment. And so the nervous system, when it becomes dysregulated in its responses, it's going to cause dysregulation of all the other symptoms and systems." "Why would I want to be in my body? My body is in pain, emotional pain, physical pain. I don't like my body. My body is working against me. At least that's the thought that I have. Why would I want to be in my body?" "That's not resilience. That's pushing through, that's surviving. So let's call it that. Let's call it, Hey, you're surviving, you're pushing through. But that kind of resilience is going to come at a cost." "Epigenetics do get passed down to us, and it gets passed down, especially through the mother because of the mitochondrial DNA that gets passed on to the children." "You actually don't have to do that much of each to start seeing shifts. But we do need to bring in all three because when you have all three, they're like small hinges. And when you've got small hinges and you've got three of these small, you just did baby steps, small hinges move big doors in our life." Episode Takeaway: Living with a genetic condition doesn't mean you're powerless over your symptoms. Your nervous system acts as the master conductor of your biology, determining how severely you experience your hereditary condition. When you have genetic vulnerabilities, your nervous system perceives them as threats and moves into trauma biology faster, creating dysregulation across all systems. The exhaustion many people feel isn't just from their disease—it's amplified by stored trauma, nervous system dysregulation, and the survival mechanism of disconnecting from their body. True healing requires removing blocks at three levels simultaneously: addressing self-limiting beliefs through parts work, completing interrupted protective responses through somatic work, and supporting cellular function through biology interventions. When you provide support across all three levels, small interventions create remarkable shifts. Your body has innate healing capacity—when blocks are removed, it can reorganize, reset, and return to its best possible state, regardless of genetic vulnerabilities. Resources/Guides: The Biology of Trauma book - Available now everywhere books are sold. Get your copy Foundational Journey - If you are ready to create your inner safety and shift your nervous system, join me and my team for this 6 week journey of practical somatic and mind-body inner child practices. Lay your foundation to do the deeper work safely and is the pre-requisite for becoming a Biology of Trauma professional.. Related Episodes: Episode 118: How Practitioners Can Navigate Their Own Chronic Illness and Healing Journey Episode 128: How Attachment Trauma Drives Anxiety, Autoimmunity & Chronic Illness Related YouTube videos: Trauma: Genetic vs. Epigenetic Insights with Dr. Bruce Lipton | Dr. Aimie Apigian   Your host: Dr. Aimie Apigian, double board-certified physician (Preventive/Addiction Medicine) with master's degrees in biochemistry and public health, revolutionizes trauma healing by revealing how our cells—not just our minds—store trauma. Her book "The Biology of Trauma" (foreword by Gabor Maté) transforms our understanding of how the body experiences and holds trauma. After adopting a child during medical school sparked her journey, she developed an integrative science-based sequence for the healing journey. Through her practitioner training, podcast, YouTube channel, and international speaking, she bridges functional medicine, attachment and trauma therapy, proving that repairing trauma's impact on the mind, body and biology is possible. Disclaimer: By listening to this podcast, you agree not to use this podcast as medical, psychological, or mental health advice to treat any medical or psychological condition in yourself or others. This podcast is for informational and educational purposes only and does not constitute professional advice, diagnosis, or treatment. Always consult your own physician, therapist, psychiatrist, or other qualified health provider regarding any physical or mental health issues you may be experiencing. Comment Etiquette: I would love to hear your thoughts on this episode! Please share your constructive feedback by using personal name or initials so that we can keep this space spam-free, and let's keep the discussion positive!
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O The Biology of Trauma® With Dr. Aimie

People are done dancing around the topic of trauma. They're ready to face this square-on. None of the current systems are getting to the root of the issue in the current model. Their biology has been affected on a cellular level, and that is now what's preventing the important work that they're trying to do. The Biology of Trauma® podcast is the missing piece to that puzzle. It's a practical living manual for the human body in a modern, traumatizing world. Join your host medical physician and attachment, trauma and addiction expert, Dr. Aimie as she challenges the old paradigm of trauma and illuminates a new model for the healing journey.
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