The Rounds Table

• TBT - The Top 5 Papers of 2024

  Send us a textWelcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2024:Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (FINEARTS-HF) (0:00 – 4:09)Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA) (4:10 – 9:28)Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (FLOW) (9:29 – 14:23)Tirzepatide for Metabolic-Dysfunction Associated Steatohepatitis with Liver Fibrosis (SYNERGY-NASH) (14:24 – 20:28)Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (BALANCE) (20:29 – 23:59)And for the Good Stuff:Toronto Star Santa Claus Fund, Calgary Food Bank, Epilepsy Canada (24:00 - 25:23)Calling keen trainees!Trainees, med students, residents: The Rounds Table and Trial Files (https://trialfiles.substack.com/) are looking for keen individuals to support our efforts.Reach out to [email protected] if you are interested in getting involved. Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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• Episode 128 - Finerenone with SGLT2 inhibitors for CKD and Type 2 Diabetes

  Send us a textWelcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the simultaneous initiation of SGLT2 inhibitors and finerenone (a nonsteroidal mineralocorticoid receptor antagonist) in persons with chronic kidney disease and type 2 diabetes. Here we go!Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes (0:00 – 9:28).Calling keen trainees! (9:29 - 10:28)Trainees, med students, residents: The Rounds Table and Trial Files are looking for keen individuals to support our efforts.Trial Files is a free monthly newsletter on practice-changing trials, delivered straight to your inbox (https://trialfiles.substack.com/).Reach out to [email protected] if you are interested in getting involved. Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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• Episode 127 - Leukocytoclastic Vasculitis with Karim Ladak

  Send us a textWelcome back Rounds Table Listeners! We are back this week with a special podcast episode. Dr. Mike Fralick sits down with Dr. Karim Ladak—rheumatologist and internist, Clinical Assistant Professor at McMaster University, and host of the Rheumatology for the Royal College podcast—to talk about leukocytoclastic vasculitis. Here we go!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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• Episode 126 - Sotatercept for Pulmonary Arterial Hypertension

  Send us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial exploring the effects of add-on sotatercept in patients with advanced pulmonary arterial hypertension and a high risk of death. Here we go!Sotatercept in Patients with Pulmonary Arterial Hypertension at High Risk for Death (0:00 – 5:38).The Good Stuff:2025 Scripps National Spelling Bee winning word: éclaircissement (5:39 - 6:34)Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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• Episode 125 - Top Papers from the 2025 American Diabetes Association (ADA) Session

  Send us a textWelcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast. This week, Dr. Mike Fralick and guest host Danielle Cutler discuss the top papers from the 2025 American Diabetes Association (ADA) Scientific Session. Hot off the presses, here we go!Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity — A Phase 2 Trial (0:00 - 6:05)Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes (6:06 - 13:22)Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes (13:23 - 20:35)The Good Stuff:Diabetes Trial Files - Free monthly newsletter! Subscribe at https://diabetestrialfiles.substack.com/ (20:36 - 21:00)Congrats to Danielle and all the med students finishing their academic year! (21:01 - 21:57)Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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