A pinch of salt - A podcast by ERA

Join A pinch of salt, as we sit down with David Jayne to trace the rapid transformation of ANCA-associated vasculitis care. From the historic cyclophosphamide–glucocorticoid backbone to biologics like rituximab and newer targeted strategies such as complement inhibition (including avacopan), this episode unpacks how clinicians can balance efficacy, safety, and quality of life—while looking ahead to what may define the next decade of treatment.

In this episode of A pinch of salt we’ll be talking to Paul Cockwell about patient-reported outcomes in clinical practice. You may or may not be aware of these issues and their importance but one might argue, and we certainly would, that every doctor should be mindful of what their patients consider to be an important outcome and whether they are achieving it or not. Paul is a champion of this field, and he provided some very useful pointers on how a beginner in this field might get to know it and start working on these issues in his or her clinical practice. The SONG initiative will be mentioned, as well as a useful systematic review on symptom burden and health-related quality of life in CKD, and a shout out to a recent important paper published in CKJ (doi: 10.1093/ckj/sfaf112). Learn about the art of trying to meet the patients’ needs in this knowledge-packed episode.

In this episode of A pinch of salt, we welcome Pierre Delanaye for a forward-looking discussion on how we should assess kidney function in 2026. Together, we explore the strengths and limits of today’s GFR equations (MDRD, CKD-EPI, cystatin C-based approaches), the promise of emerging biomarkers and AI-driven tools, and the crucial question of fairness and accuracy across diverse populations.

In this episode of A pinch of salt, Shuchi Anand will talk about chronic kidney disease of unknown etiology, the mysterious kidney disease that is devastating some agricultural communities in hot environments. Dr Anand will talk about what might be causing this disease, does a kidney biopsy help, is it mandatory, and how to treat these patients both on the individual level and on the population level to tackle this disease locally and globally. Learn more about this true medical mystery, with stories from the literature and stories from the field.