TikTok was founded just six years ago and is already one of the leading social media platforms, becoming the world’s most downloaded app in 2020. It has more than one billon monthly active users and is especially popular with teens and young adults, with 42% of TikTok users aged between 18 and 24. 5 Live Breakfast has been looking at the impact of TikTok as the platform’s popularity continues to rise. TOPICS: 01:43 – Shiona McCallum, a BBC Technology Reporter 04:03 – Jan Gerber, CEO and founder a mental health and addiction clinic 09:25 – Mesha Moinirad - otherwise known as Mr Colitis Crohn’s 14:41 – Influencer Seema Pankhania, content creator and recipe developer 17:58 - Sophie O’Sullivan, in recovery from anorexia and Tom Quinn, Director of External Affairs at the Eating Disorder charity BEAT 25:12 - Sam Ryder, musician and Eurovision star 28:03 - Marianna Spring, BBC’s Specialist Disinformation reporter 33:53 – Zeynab Mohamed who thought she had OCD after watching videos on platforms like TikTok and clinical psychologist Jane Gilmore 40:20 – Reporter Mark Hutchings speaking to a group of 15-year-old pupils at Pen y Dre High School in Merthyr

On Tuesday night, Prime Minister Boris Johnson's premiership plunged into crisis following the dramatic resignations of Chancellor Rishi Sunak and Health Secretary Sajid Javid. They quit within minutes of each other on following a row over Mr Johnson's decision to appoint Chris Pincher as deputy chief whip earlier this year. After a further flurry of resignations on Wednesday morning, the prime minister faced fierce questioning in the House of Commons for what was sure to be a heated edition of PMQs. Following this, Sajid Javid spoke to the House to give his resignation speech after quitting as health secretary last night. With analysis from Editor of The House Magazine, Rosa Prince, and Parlimentary Correspondent Sean Curran.

Former elite gymnast Clare Heafford, Guardian sports reporter Sean Ingle and Rachael Denhollander, the first woman to publicly accuse US Gymnastics Doctor Larry Nassar of sexual abuse, join Colin Murray to discuss The Whyte Review.

Radio 1 DJ Adele Roberts has recently finished a round of chemotherapy for bowel cancer and is now living with a stoma. She spoke to 5 Live’s Naga Munchetty about everything from naming her stoma, feeling sexy again and how cancer treatment has changed her relationship with her body.

Dr Waheed Arian, a former refugee from Afghanistan, now an A&E doctor, wanted to hear stories from other people like him. He is working to help improve the accessibility of mental health services for refugees like himself. One of the people he spoke to was Nataliia from Ukraine, who arrived in the UK along with her six-year-old daughter a couple of months ago.