The Dr. Tyna Show

EP. 259: What if one compound from broccoli could influence detox pathways, estrogen metabolism, gut integrity, and even how your body handles modern environmental toxins like microplastics?

In this episode, I sit down with David Roberts and Dr. John Gilday from Mara Labs to break down sulforaphane and why it plays such a unique role in metabolic and hormonal health.

We talk about estrogen metabolism, NRF2 activation, inflammation signaling, gut barrier function, and emerging research around microplastics and cellular detox systems.→ For the next week, Dr Tyna Show loyal listeners can get an exclusive 25% off all Mara Labs products when you go to www.mara-labs.com/DRTYNA and use code DRTYNA at checkout. After May 7th, the code will return to the standard 15% off.

Topics Discussed:

→ How does sulforaphane affect detox pathways

→ What does NRF2 do in the body

→ Can supplements help estrogen metabolism

→ How do microplastics affect hormones

→ What improves gut barrier function

Sponsored By:

→ Mara Labs | For the next week, Dr Tyna Show loyal listeners can get an exclusive 25% off all Mara Labs products when you go to www.mara-labs.com/DRTYNA and use code DRTYNA at checkout. After May 7th, the code will return to the standard 15% off.

On This Episode We Cover: 

→ 00:00:00 - Introduction 

→ 00:03:32 - Estrogen + Metabolism  

→ 00:06:54 - AMPK + SIRT 1  

→ 00:12:42 - Supplement Comparisons 

→ 00:17:47 - Cooked vs Raw Broccoli 

→ 00:23:33 - Detox Phases 

→ 00:27:13 - Microdosing GLP1 

→ 00:29:11 - Leaky Gut + Glyphosate 

→ 00:31:51 - Sauna + Red Light 

→ 00:34:21 - Alcohol + Hangovers 

→ 00:35:18 - Exercise Performance + Recovery

→ 00:39:12 - Joint Pain + Osteoporosis  

→ 00:42:16 - Middle Age Mental Health 

→ 00:46:54 - Antimicrobials + Gut 

→ 00:49:13 - Metabolic Health 

→ 00:57:30 - The Gut Barrier 

→ 01:00:12 - Impacts of Microplastics

→ 01:05:07 - Microplastic Detox 

→ 01:07:27 - Micropastic Study 

→ 01:11:17 - Supplement Stacking 

→ 01:12:10 - Skincare + Gut 

→ 01:17:03 - Bacteria + Inflammation 

→ 01:18:33 - Menopause Benefits   

Check Out Mara Labs:

→ For the next week, Dr Tyna Show loyal listeners can get an exclusive 25% off all Mara Labs products when you go to www.mara-labs.com/DRTYNA and use code DRTYNA at checkout. After May 7th, the code will return to the standard 15% off.

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

EP. 258: Get Strong with Me Inside my NEW Strength Vault: https://www.drtyna.com/offers/G33fSdvSIn this episode, I’m breaking down one of the most frustrating conversations happening in women’s health right now, the claim that estrogen and hormone replacement therapy don’t support muscle mass.

The reality is more nuanced.

I walk through what the current research actually shows, where it’s strong, where it’s inconsistent, and how estrogen interacts with skeletal muscle at a physiological level. We’re talking about estrogen receptors in muscle, mitochondrial function, anabolic signaling, insulin resistance, and why outcomes around muscle are often context-dependent.

I also share what I’ve observed clinically after decades of working in a musculoskeletal setting, and how factors like metabolic health, training status, and overall tissue quality may influence how hormone therapy plays out in the real world.

This episode isn’t about claiming HRT builds muscle. It’s about understanding how estrogen affects muscle biology, and why strength training remains a non-negotiable piece of the equation.

Topics Discussed:

→ Estrogen and muscle growth

→ HRT and menopause fitness

→ Strength training for women over 40

→ Insulin resistance and muscle health

→ Hormones and metabolic health

Sponsored By:

→ Ogee | Thanks to today’s sponsor, Ogee: A higher standard for beauty. Go to https://ogee.com/DRTYNA and use code DRTYNA to get 15% off certified organic makeup that performs like luxury. 

→ EnergyBits | If you want a simpler, smarter way to support your body… this is it. Head to https://ENERGYbits.com and use code DTS for 20% off your order. 

→ Puori | Go to https://puori.com/DRTYNA and use the code DRTYNA at checkout to get 32% off your first Protein subscription order and get a free shaker worth $25.

→ BIOptimizers | For an exclusive offer, go to https://bioptimizers.com/drtyna and use code DRTYNA for 15% off + a FREE MassZymes bottle. Limited time, while supplies last.

→ Timeline | Timeline’s clinically proven formula is now available at a new, lower price. Mitopure now starts at $79, when you go to https://timeline.com/drtyna

→ Sundays | Make the switch to Sundays. Go right now to https://sundaysfordogs.com/DRTYNA50 and get 50% off your first order. Or, you can use code DRTYNA50 at checkout.

On This Episode We Cover: 

→ 00:00:00 - Introduction 

→ 00:01:24 - HRT Misinformation 

→ 00:03:20 - Rejentivite Injection Therapy + HRT 

→ 00:06:48 - You Must Strength Train 

→ 00:07:57 - Scientific Overview 

→ 00:11:19 - Building Skeletal Muscle 

→ 00:14:47 - Estrogen’s Impact On Muscle 

→ 00:19:44 - HRT + Metabolic Health 

→ 00:24:05 - Estrogen + Muscle Pathways 

→ 00:26:57 - Why Muscle Suddenly Disappears

→ 00:29:52 - Insulin Resistance 

→ 00:36:36 - Quality Of Life Improvement 

→ 00:40:25 - Post Menopausal Studies 

→ 00:40:25 - Improving HRT 

→ 00:44:26 - HRT + Muscle Environment 

Show Links: 

→ Transdermal Estrogen Therapy Improves Gains in Skeletal Muscle Mass After 12 Weeks of Resistance Training in Early Postmenopausal Women

→ The role of estrogen in female skeletal muscle aging: A systematic review

→ Mechanisms of Estrogen Influence on Skeletal Muscle: Mass, Regeneration, and Mitochondrial Function

→ Muscle in Endocrinology: From Skeletal Muscle Hormone Regulation to Myokine Secretion and Its Implications in Endocrine–Metabolic Diseases

→ New Meta-Analysis Shows That Hormone Therapy Can Significantly Reduce Insulin Resistance

Further Listening: 

→ The TRUTH Behind Menopausal Pain & What You Can Do About It | Ep 256

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

EP. 257: Grab my brand new Strength Vault: https://www.drtyna.com/offers/G33fSdvS

Frailty is something most people don’t think about until it’s too late, but it’s one of the biggest predictors of whether you survive illness, recover from injury, or maintain independence as you age. It’s also the harbinger of doom for all cause mortality and dementia.

In this episode, I break down why frailty isn’t just “getting older”, it’s a metabolic and muscular decline that starts earlier than you think and accelerates fast if you’re not actively fighting it.

I share a personal story about my mom’s recent hospitalization and how quickly muscle loss and weakness can set in, even in someone who seems active. We also dig into the science behind frailty, its connection to metabolic health, dementia, and mortality, and why muscle is your greatest protective organ.

If you care about staying independent, avoiding hospital decline, and actually thriving as you age, this is a conversation you need to hear.

Topics Discussed:

→ What causes frailty as you age

→ How to prevent muscle loss after 50

→ Why is frailty dangerous in aging

→ Can you reverse frailty naturally

→ What are early signs of frailty

Sponsored By:

→ Sunlighten | Learn more at https://sunlighten.com/drtyna and use code DRTYNASHOW to save up to $1,400 on your sauna purchase with additional savings throughout the year. 

→ LMNT | Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at https://drinklmnt.com/drtyna. Find your favorite LMNT flavor, or share with a friend.

→  Fatty15 | You can get an additional 15% off their 90-day subscription Starter Kit by going to https://fatty15.com/DRTYNA and using code DRTYNA at checkout. 

→ Cozy Earth | Let this Mother’s Day be a reminder that she deserves care, too. Discover how Cozy Earth turns everyday routines into moments of softness and ease. Head to https://cozyearth.com and use my code DRTYNA for an exclusive 20% off.

→ BIOptimizers | For an exclusive offer, go to https://bioptimizers.com/drtyna and use code DRTYNA for 15% off + a FREE MassZymes bottle. Limited time, while supplies last.

→ Manukora | Head to https://manukora.com/DRTYNA to save up to 31% plus $25 worth of free gifts with the Starter Kit, which comes with an MGO 850+ Manuka Honey jar, 5 honey travel sticks, a wooden spoon, and a guidebook!

On This Episode We Cover: 

→ 00:00:00 - Introduction 

→ 00:05:05 - Normalizing Frailty → 00:06:17 - Farming + Active Lifestyles

→ 00:07:49 - How Frailty Starts

→ 00:11:07 - How Illness Rapidly Destroys Muscle

→ 00:14:57 - Personal Story: Hospitalization Wake-Up Call

→ 00:18:23 - When Frailty Starts

→ 00:20:22 - The Muscle-Metabolism Connection

→ 00:23:42 - Dangers Of “Thin Is In”

→ 00:30:48 - Elderly Weight Loss

→ 00:36:22 - Defining Frailty + Warning Signs

→ 00:43:61 - HRT + Sleep Health

→ 00:48:34 - Science + Statistic

→ 00:53:49 - What You Can Actually Do

Show Links: 

→ Find A Doc 

→ Metabolic Revamp TookKit 

→ NEW: Strength Vault  

→ Dr Tyna App | Apple

→ Dr Tyna App | Google 

Further Listening: 

→ EP. 222 | How to Build Muscle and Look Younger After 50 (Even for Beginners) | JJ Virgin

→ EP. 149: You Need To Take The Stairs | Quick + Dirty

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

EP. 256: In this episode, I'm sharing my personal hormone journey and what decades of clinical experience treating fit, healthy, middle-aged patients taught me about HRT, menopause, and why so many perimenopausal and menopausal women are suffering unnecessarily.

After years of working with highly fit, health-conscious patients, I saw a clear pattern: as hormones decline, even the most disciplined women can experience sudden weight gain, chronic pain, injuries that won't heal, and devastating mental and emotional shifts.

Topics Discussed:

→ What are the real benefits of HRT for women over 40?

→ Can low estrogen cause joint pain and injuries?

→ Why do fit women struggle during menopause?

→ How does hormone imbalance affect mental health?

→ When should you start hormone replacement therapy?

Sponsored By:

→ Timeline | Timeline’s clinically proven formula is now available at a new, lower price. Mitopure now starts at $79, when you go to https://timeline.com/drtyna

→ KION | Visit https://getkion.com/drtyna for 20% off

→ LMNT | Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at https://drinklmnt.com/drtyna. Find your favorite LMNT flavor, or share with a friend.

→ Sundays | Make the switch to Sundays. Go right now to https://sundaysfordogs.com/DRTYNA50 and get 50% off your first order. Or, you can use code DRTYNA50 at checkout.

→ BIOptimizers | For an exclusive offer, go to https://bioptimizers.com/drtyna and use promo code DRTYNA during checkout to save 15%.

→ Manukora | Head to https://manukora.com/DRTYNA to save up to 31% plus $25 worth of free gifts with the Starter Kit, which comes with an MGO 850+ Manuka Honey jar, 5 honey travel sticks, a wooden spoon, and a guidebook!

On This Episode We Cover: 

→ 00:00:00 - Introduction 

→ 00:01:30 - Dr. Tyna’s Clinical Experience 

→ 00:04:53 - Online Opinions + Joint Pain 

→ 00:12:59 - Middle Age Health 

→ 00:16:22 - Joint Health Research 

→ 00:18:11 - Weight Gain + Chronic Pain 

→ 00:25:36 - High End Medical Treatment 

→ 00:30:11 - Hitting Perimenopause 

→ 00:33:12 - Pain + Insomnia 

→ 00:37:50 - Transdermal Estrogen 

→ 00:40:21 - Hormones + The Gym 

Further Listening: 

→ What Women NEED To Know to Optimize Their Hormones For Health for Vitality & Longevity | Ep. 241

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

EP. 255: Low estrogen can show up in subtle, unexpected ways that often go unnoticed or dismissed, even by healthcare providers.

In this episode, I’m breaking down 5 hazardous signs of low estrogen that could be impacting your daily life more than you realize. From joint pain and brain fog to mood swings, anxiety, and depression, these symptoms are often misunderstood but deeply connected to hormonal health.

Topics Discussed:→ What are signs of low estrogen?

→ Can low estrogen cause anxiety symptoms?

→ Why does low estrogen cause brain fog?

→ Does low estrogen cause joint pain?

→ What does hormonal imbalance feel like?

Sponsored By:

→ BIOptimizers | For an exclusive offer, go to https://bioptimizers.com/drtyna and use promo code DRTYNA during checkout to save 15%.

→ Puori | Go to https://puori.com/DRTYNA and use the code DRTYNA at checkout to get 32% off your first Protein subscription order and get a free shaker worth $25.

→ Manukora | Head to https://manukora.com/DRTYNA to save up to 31% plus $25 worth of free gifts with the Starter Kit, which comes with an MGO 850+ Manuka Honey jar, 5 honey travel sticks, a wooden spoon, and a guidebook!

→ LMNT | Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase at https://drinklmnt.com/drtyna Find your favorite LMNT flavor, or share with a friend.

On This Episode We Cover:

→ 00:00:00 - Introduction 

→ 00:00:38 - Dr. Tyna’s experience with HRT 

→ 00:06:31 - Why doctors do and don't utilize hormones 

→ 00:08:18 - Estrogen and metabolic issues 

→ 00:10:07 - Chronic stress and hormone levels 

→ 00:15:56 - Seeking professional help 

→ 00:19:02 - Medically induced menopause (hysterectomy) 

→ 00:21:15 - Estrogen decline and pain 

→ 00:23:38 - Joint health & insulin resistance 

→ 00:30:42 - Blood flow 

→ 00:31:33 - Ripping of tendons and ligaments 

→ 00:32:15 - Brain fog 

→ 00:33:33 - Devastating depression 

→ 00:37:09 - All consuming anxiety 

→ 00:40:55 - Labial and facial aging 

Show Links: 

→ Finding a Good Doc Free Video Training

→ Assess Your Metabolic Health Free Guide

Further Listening:

→ 173: Why Women Shouldn’t Wait: My Top 6 Reasons to Start Hormone Replacement Therapy Early | Solo

→ 91: Thyroid Secrets Your Doctor Doesn't Know | Solo Episode

→ 86: Orthopedic Medicine is a Scam PT 3: Osteoarthritis is Diabetes of the Joint

Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.